Gonadorelin (CAS 33515-09-2) – Wholesale & Research Grade
Gonadorelin is a ten-membered synthetic oligopeptide comprising pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, glycyl, leucyl, arginyl, prolyl and glycinamide residues joined in sequence. It has a role as a gonadotropin releasing hormone agonist. It is an oligopeptide and a peptide hormone.
Research Context
Gonadorelin, a synthetic analog of gonadotropin-releasing hormone (GnRH), plays a crucial role in reproductive health research and clinical applications. It is commonly used in studies related to the regulation of the hypothalamic-pituitary-gonadal (HPG) axis, making it invaluable in both animal models and human trials. Researchers often utilize Gonadorelin for its ability to stimulate the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which are essential for normal reproductive function.
Mechanism of Action
The primary mechanism of action of Gonadorelin involves its binding to GnRH receptors in the pituitary gland, leading to the secretion of LH and FSH. This action is pivotal for initiating the gonadal steroidogenesis process, thereby influencing spermatogenesis in males and ovarian function in females. As a result, Gonadorelin is frequently employed in fertility treatments and protocols for assisted reproductive technologies, such as in vitro fertilization (IVF).
Solubility and Storage Advice
Gonadorelin is soluble in water and can be stored at controlled room temperature. For long-term storage, it is advisable to keep the compound in a cool, dry place, protected from light. Stability can be enhanced by using appropriate buffers during experiments, and it should be reconstituted immediately before use to maintain its biological activity.
Future Research Directions
- Investigating the role of Gonadorelin in various reproductive disorders, such as hypogonadism and polycystic ovary syndrome (PCOS).
- Exploring its potential applications in hormone replacement therapies and managing precocious puberty.
- Developing novel delivery systems to enhance the efficacy and stability of Gonadorelin in clinical settings.
Overall, ongoing research into Gonadorelin's applications continues to uncover its potential in reproductive medicine and offers promising avenues for future therapeutic strategies.
| CAS Number | 33515-09-2 |
|---|---|
| Formula | C55H75N17O13 |
| Mol. Weight | 1182.3 g/mol |
| IUPAC Name | (2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[(2S)-2-[(2-a... |
| Grade | HPLC ≥98% |
Synthesis & Storage
Gonadorelin is supplied as a lyophilized powder to ensure stability during transit.
For long-term storage of CAS 33515-09-2, we recommend maintaining at -20°C.
Researchers must reconstitute this peptide with bacteriostatic water or sterile solvent only when ready for use.
Quality Control: All batches undergo rigorous HPLC purity testing (≥98%) prior to dispatch from our USA fulfillment center.