Cibinetide (CAS 1208243-50-8) – Wholesale & Research Grade
Cibinetide, also known as ABX-181 or KYN-190, is a synthetic peptide with promising applications in the field of biomedical research, particularly in neurodegenerative diseases and cognitive disorders. Its unique properties have garnered attention for potential therapeutic uses in modulating inflammatory processes and enhancing neuroprotection.
Research Applications
Cibinetide has been primarily investigated for its role in neuroprotection and the treatment of conditions such as Alzheimer’s disease. Studies have shown that it may support cognitive function by promoting neuronal health and reducing inflammation in the brain. Its applications extend to animal models of various neurodegenerative diseases, where it has demonstrated the capacity to improve cognitive performance and delay the progression of symptoms.
Mechanism of Action
The mechanism of action of Cibinetide involves the modulation of neuroinflammatory pathways and enhancement of synaptic plasticity. It is believed to interact with receptors involved in the regulation of neurotrophic factors, subsequently facilitating neuronal survival and repair. This action helps mitigate the harmful effects of neuroinflammation, a common hallmark in various neurodegenerative disorders.
Solubility and Storage Advice
Cibinetide is soluble in aqueous solutions, which facilitates its use in various experimental settings. For optimal stability, it should be stored at -20°C in a dry, dark environment to prevent degradation. Avoiding repeated freeze-thaw cycles is essential to maintain its integrity for future research applications.
Future Research Directions
- Further investigation into Cibinetide's efficacy in clinical trials for Alzheimer’s and other cognitive disorders.
- Exploration of its potential as a therapeutic agent in other neuroinflammatory conditions.
- Development of new formulations to enhance bioavailability and delivery methods.
As research continues, Cibinetide holds the promise of advancing our understanding and treatment of neurodegenerative diseases, opening new avenues for therapeutic intervention.
| CAS Number | 1208243-50-8 |
|---|---|
| Formula | C51H84N16O21 |
| Mol. Weight | 1257.3 g/mol |
| IUPAC Name | (4S)-5-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4... |
| Grade | HPLC ≥98% |
Synthesis & Storage
Cibinetide is supplied as a lyophilized powder to ensure stability during transit.
For long-term storage of CAS 1208243-50-8, we recommend maintaining at -20°C.
Researchers must reconstitute this peptide with bacteriostatic water or sterile solvent only when ready for use.
Quality Control: All batches undergo rigorous HPLC purity testing (≥98%) prior to dispatch from our USA fulfillment center.