MK 0677 (CAS 159752-10-0) – Wholesale & Research Grade
MK 0677, also known as ibutamoren or L-163,191, has garnered attention in the field of biomedical research due to its unique properties as a potent growth hormone secretagogue. This compound is primarily studied for its ability to stimulate the secretion of growth hormone, thereby enhancing muscle growth and promoting fat loss. Its potential applications extend to various fields, including endocrinology, gerontology, and sports medicine.
Research Applications
Research involving MK 0677 has predominantly focused on its role in muscle wasting disorders, obesity, and age-related conditions. In clinical studies, it has shown promise in improving body composition and metabolic health, making it a candidate for therapies aimed at countering sarcopenia and cachexia. Additionally, its anabolic effects have sparked interest in the athletic community, highlighting the need for further investigation into its safety profile and long-term effects.
Mechanism of Action
The mechanism of action of MK 0677 involves its interaction with the ghrelin receptor, leading to an increase in endogenous growth hormone levels. This action not only promotes muscle hypertrophy but also enhances energy expenditure, influencing overall body composition. The compound's selective stimulation of growth hormone release distinguishes it from traditional anabolic agents, offering a novel approach to muscle enhancement and metabolic regulation.
Solubility and Storage
MK 0677 exhibits solubility in organic solvents such as ethanol and dimethyl sulfoxide (DMSO), which are commonly used in laboratory settings. For optimal stability, it is recommended to store the compound in a cool, dry place, protected from light. Proper storage conditions are vital to maintaining its efficacy for research applications.
Future Research Directions
Future research on MK 0677 is poised to explore its long-term safety and efficacy in diverse populations, including older adults and those with metabolic disorders. Investigations into its pharmacokinetics and potential off-target effects will be crucial in establishing a comprehensive understanding of its therapeutic profile. As interest in growth hormone secretagogues continues to rise, MK 0677 may play a pivotal role in advancing treatment options for various health conditions.
| CAS Number | 159752-10-0 |
|---|---|
| Formula | C28H40N4O8S2 |
| Mol. Weight | 624.8 g/mol |
| IUPAC Name | 2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-... |
| Grade | HPLC ≥98% |
Synthesis & Storage
MK 0677 is supplied as a lyophilized powder to ensure stability during transit.
For long-term storage of CAS 159752-10-0, we recommend maintaining at -20°C.
Researchers must reconstitute this peptide with bacteriostatic water or sterile solvent only when ready for use.
Quality Control: All batches undergo rigorous HPLC purity testing (≥98%) prior to dispatch from our USA fulfillment center.