Pralmorelin (CAS 158861-67-7) – Wholesale & Research Grade
Pralmorelin is an oligopeptide.
Research Context
Pralmorelin, commonly referred to as MK-0677 or GHRP-2, is a growth hormone secretagogue that has gained significant attention in the field of clinical research. Its primary application lies in stimulating growth hormone release, making it a valuable compound for studies related to growth disorders, metabolic diseases, and age-related conditions.
Research Applications
In various preclinical and clinical studies, pralmorelin has been investigated for its potential to enhance anabolic processes, support muscle mass retention, and promote fat metabolism. Researchers are particularly interested in its effects on patients experiencing cachexia or muscle wasting due to chronic illnesses. Additionally, its role in stimulating appetite has made it a candidate for studies focusing on weight gain in patients with severe conditions.
Mechanism of Action
Pralmorelin functions by selectively binding to the ghrelin receptor, mimicking the action of ghrelin, a naturally occurring hormone. This interaction triggers a cascade of biochemical events that enhance the secretion of growth hormone from the pituitary gland. By activating these pathways, pralmorelin not only augments growth hormone levels but also promotes metabolic effects that are beneficial in various therapeutic contexts.
Solubility and Storage Advice
Pralmorelin is soluble in organic solvents and exhibits limited solubility in water, which is an important consideration for formulation and administration. For optimal stability and efficacy, it should be stored in a cool, dry place, protected from light. Refrigeration is recommended to maintain its integrity over time, and precautions should be taken to avoid exposure to moisture.
Future Research Directions
Future research on pralmorelin is poised to expand its potential applications beyond growth hormone deficiency. Investigations into its role in metabolic syndrome, obesity management, and its therapeutic impact on age-related muscle loss are of significant interest. Additionally, exploring novel formulations and delivery methods may enhance its bioavailability and therapeutic efficacy, paving the way for new clinical applications.
| CAS Number | 158861-67-7 |
|---|---|
| Formula | C45H55N9O6 |
| Mol. Weight | 818.0 g/mol |
| IUPAC Name | (2S)-6-amino-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-aminopropanoyl]am... |
| Grade | HPLC ≥98% |
Synthesis & Storage
Pralmorelin is supplied as a lyophilized powder to ensure stability during transit.
For long-term storage of CAS 158861-67-7, we recommend maintaining at -20°C.
Researchers must reconstitute this peptide with bacteriostatic water or sterile solvent only when ready for use.
Quality Control: All batches undergo rigorous HPLC purity testing (≥98%) prior to dispatch from our USA fulfillment center.