Octreotide (CAS 83150-76-9) – Wholesale & Research Grade
Octreotide, a synthetic analog of somatostatin, is widely utilized in research and clinical applications due to its potent inhibitory effects on various endocrine and exocrine secretions. Researchers are particularly interested in its role in managing conditions such as acromegaly, neuroendocrine tumors, and other disorders characterized by excessive hormone production.
Research Applications
This compound has been pivotal in studies related to endocrine regulation and tumor biology. Its ability to reduce growth hormone levels makes it a key substance in experiments aimed at understanding the pathophysiology of growth hormone-secreting tumors. Furthermore, Octreotide is employed in the treatment of carcinoid syndrome, where it alleviates flushing and diarrhea caused by vasoactive intestinal peptide (VIP) secreting tumors.
Mechanism of Action
Octreotide exerts its therapeutic effects by binding to somatostatin receptors, particularly subtype 2 and 5, which are prevalent in various tissues. This binding inhibits the secretion of multiple hormones including insulin, glucagon, and growth hormone. The resultant decrease in hormone levels not only mitigates symptoms but may also slow tumor growth in certain malignancies. The mechanism of action is critical for researchers exploring targeted therapies and endocrine signaling pathways.
Solubility and Storage Advice
In terms of solubility, Octreotide is soluble in aqueous solutions, making it suitable for various experimental setups. However, it is recommended to store the compound at -20°C to maintain stability and efficacy over time. Protecting it from light and moisture is crucial to prevent degradation, ensuring reliable results in research applications.
Future Research Directions
Looking ahead, the potential for Octreotide in combination therapies is an exciting avenue for research, particularly in the context of novel cancer treatments and metabolic disorders. Ongoing studies aim to elucidate its effects on different somatostatin receptor subtypes, which could pave the way for more selective therapies. Further investigation into its pharmacokinetics and long-term effects will also enhance understanding of its role in clinical settings.
| CAS Number | 83150-76-9 |
|---|---|
| Formula | C49H66N10O10S2 |
| Mol. Weight | 1019.2 g/mol |
| IUPAC Name | (4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-19-[[(2R)-2-amino-3-phenylpropanoyl... |
| Grade | HPLC ≥98% |
Synthesis & Storage
Octreotide is supplied as a lyophilized powder to ensure stability during transit.
For long-term storage of CAS 83150-76-9, we recommend maintaining at -20°C.
Researchers must reconstitute this peptide with bacteriostatic water or sterile solvent only when ready for use.
Quality Control: All batches undergo rigorous HPLC purity testing (≥98%) prior to dispatch from our USA fulfillment center.