Glutathione (CAS 70-18-8) – Wholesale & Research Grade
Glutathione is a tripeptide compound consisting of glutamic acid attached via its side chain to the N-terminus of cysteinylglycine. It has a role as a skin lightening agent, a human metabolite, an Escherichia coli metabolite, a mouse metabolite, a geroprotector, an antioxidant and a cofactor. It is a tripeptide, a thiol and a L-cysteine derivative. It is a conjugate acid of a glutathionate(1-).
Research Context
Glutathione, also known as GSH or reduced glutathione, is a tripeptide composed of three amino acids: cysteine, glutamine, and glycine. It plays a crucial role in various biological processes, including antioxidant defense, detoxification, and the maintenance of cellular homeostasis. As a potent antioxidant, glutathione protects cells from oxidative stress by neutralizing free radicals, thereby contributing to the overall health of tissues and organs.
Research Applications
This compound is widely studied in the fields of biochemistry and molecular biology. Its applications extend to understanding mechanisms of disease, particularly in cancer, neurodegenerative disorders, and cardiovascular diseases. Researchers utilize glutathione in therapeutic interventions aimed at enhancing the body’s natural detoxification processes, promoting cellular repair, and improving immune function.
Mechanism of Action
Glutathione functions primarily through its ability to donate electrons to free radicals and reactive oxygen species, effectively neutralizing them. It also plays a pivotal role in the regeneration of other antioxidants, such as vitamins C and E, enhancing their efficacy. In detoxification, glutathione conjugates with harmful substances, facilitating their excretion from the body. This mechanism is vital for protecting cells against damage from environmental toxins and drugs.
Solubility and Storage Advice
Glutathione is soluble in water, making it easy to incorporate into various formulations for research and therapeutic purposes. However, it is sensitive to oxidation and should be stored in a cool, dry place away from light to maintain its stability. It is recommended to keep it in tightly sealed containers to prevent degradation.
Future Research Directions
Future studies on glutathione are likely to explore its role in aging and longevity, as well as its potential in cancer therapy. Investigating glutathione's interaction with various cellular pathways may yield insights into its application for enhancing drug efficacy and reducing side effects. Additionally, research into novel delivery systems for glutathione supplementation could open new avenues for clinical applications.
| CAS Number | 70-18-8 |
|---|---|
| Formula | C10H17N3O6S |
| Mol. Weight | 307.33 g/mol |
| IUPAC Name | (2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-1-oxo-3-sulfanylpropan-2-yl]amin... |
| Grade | HPLC ≥98% |
Synthesis & Storage
Glutathione is supplied as a lyophilized powder to ensure stability during transit.
For long-term storage of CAS 70-18-8, we recommend maintaining at -20°C.
Researchers must reconstitute this peptide with bacteriostatic water or sterile solvent only when ready for use.
Quality Control: All batches undergo rigorous HPLC purity testing (≥98%) prior to dispatch from our USA fulfillment center.