Resveratrol (CAS 501-36-0) – Research Grade is a high-purity chemical compound.

Resveratrol is a stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups. It has a role as a phytoalexin, an antioxidant, a glioma-associated oncogene inhibitor and a geroprotector. It is a stilbenol, a polyphenol and a member of resorcinols.

Research Context

Resveratrol, a natural polyphenolic compound found in various plants, particularly in the skin of red grapes and berries, has garnered significant attention in the field of biomedical research due to its potential health benefits. This compound is often associated with its role as a dietary supplement, leveraging its antioxidant properties to combat oxidative stress and inflammation.

Research Applications

Resveratrol has been extensively studied for its implications in various health-related fields, including cardiovascular health, cancer prevention, and neuroprotection. Notably, it is often explored for its potential to enhance longevity and mitigate age-related diseases by mimicking caloric restriction effects. Research has shown that resveratrol may activate certain cellular pathways, such as the SIRT1 pathway, which is linked to improved metabolic health and increased lifespan in model organisms.

Mechanism of Action

The mechanisms through which resveratrol exerts its effects are multifaceted. It is known to modulate various signaling pathways, including those involved in inflammation and cell survival. Resveratrol’s ability to activate sirtuins, a family of proteins that regulate cellular health, further underscores its role in promoting metabolic efficiency and preserving cellular function. Additionally, resveratrol has exhibited potential in inhibiting the proliferation of cancer cells through the modulation of cell cycle regulation and apoptosis.

Solubility and Storage Advice

Resveratrol is soluble in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO), but has limited solubility in water. For optimal stability, it is recommended to store resveratrol in a cool, dark place, preferably in airtight containers to prevent degradation. Protecting it from light and moisture is crucial for maintaining its efficacy over time.

Future Research Directions

Future investigations into resveratrol are poised to explore its synergistic effects with other compounds and its potential applications in chronic disease management. There is also a growing interest in its bioavailability and the development of novel delivery systems to enhance its therapeutic effects. Furthermore, clinical trials examining resveratrol's impact on human health outcomes will be vital in translating preclinical findings into practical health applications.