ACTH (4-7), Pro-Gly-Pro- (CAS 80714-61-0) – Wholesale & Research Grade
ACTH (4-7), Pro-Gly-Pro- is a peptide fragment derived from adrenocorticotropic hormone (ACTH), and it has garnered interest in various research applications, particularly in the fields of endocrinology and neurobiology. This compound is recognized for its potential role in modulating stress responses and influencing neuropeptide activity, making it a valuable tool for investigating the hypothalamic-pituitary-adrenal (HPA) axis and its associated pathways.
Research Applications
- Studying the effects of ACTH on adrenal gland function and cortisol production.
- Exploring its neuroprotective properties and potential therapeutic applications in neurodegenerative diseases.
- Investigating the modulation of immune responses and inflammatory pathways.
The mechanism of action of ACTH (4-7), Pro-Gly-Pro- is thought to involve the activation of specific receptors that are part of the corticotropin-releasing hormone system. This activation can lead to the stimulation of steroidogenesis in the adrenal cortex, as well as the modulation of neurotransmitter release in the central nervous system. Its ability to influence both endocrine and nervous systems makes it a unique subject for research into stress-related disorders.
Solubility and Storage
ACTH (4-7), Pro-Gly-Pro- is soluble in aqueous solutions, which facilitates its use in various experimental setups. For optimal stability, it is recommended to store this peptide at -20°C and protect it from light exposure. Proper handling and storage conditions are essential to maintain the integrity of the peptide for accurate experimental results.
Future Research Directions
Future research on ACTH (4-7), Pro-Gly-Pro- could explore its role in modulating behaviors related to stress and anxiety, providing insights into its therapeutic potential in psychiatric disorders. Additionally, investigating the interactions between this peptide and other neuropeptides may reveal novel pathways that could be targeted in drug development. As the understanding of this peptide's biological effects deepens, it may lead to innovative approaches in treating conditions influenced by the HPA axis.
| CAS Number | 80714-61-0 |
|---|---|
| Formula | C37H51N9O10S |
| Mol. Weight | 813.9 g/mol |
| IUPAC Name | (2S)-1-[2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-methylsulfanylb... |
| Grade | HPLC ≥98% |
Synthesis & Storage
ACTH is supplied as a lyophilized powder to ensure stability during transit.
For long-term storage of CAS 80714-61-0, we recommend maintaining at -20°C.
Researchers must reconstitute this peptide with bacteriostatic water or sterile solvent only when ready for use.
Quality Control: All batches undergo rigorous HPLC purity testing (≥98%) prior to dispatch from our USA fulfillment center.