Pramlintide Acetate (CAS 196078-30-5) – Wholesale & Research Grade
Pramlintide acetate, a synthetic analog of amylin, is primarily utilized in the management of diabetes, particularly in type 1 and type 2 diabetes patients who are on insulin therapy. Its application is significant in research settings focused on metabolic regulation and the modulation of glycemic control. As an adjunct to insulin therapy, Pramlintide acetate helps to mitigate postprandial glucose excursions, thus providing a comprehensive approach to diabetes management.
Mechanism of Action
The mechanism of action of Pramlintide acetate involves the regulation of glucose homeostasis through several pathways. It functions by slowing gastric emptying, which leads to a reduction in post-meal glucose spikes. Additionally, Pramlintide acetate enhances satiety, thereby aiding in weight management—a critical factor in diabetes care. Furthermore, it inhibits the secretion of glucagon, a hormone that raises blood glucose levels, contributing to its overall efficacy in blood sugar control.
Solubility and Storage
Pramlintide acetate is soluble in aqueous solutions, making it suitable for subcutaneous administration. For optimal stability, it should be stored in a refrigerator at temperatures between 2°C and 8°C. It is crucial to protect the solution from light and avoid freezing, as these conditions can compromise the integrity of the compound. Once opened, the solution can be kept at room temperature for a limited time, but it should always be used in accordance with the guidelines provided by the manufacturer to ensure safety and efficacy.
Future Research Directions
Future research on Pramlintide acetate is expected to explore its potential benefits beyond diabetes management, including its role in obesity treatment and its effects on cardiovascular health in diabetic patients. Investigations into combination therapies, where Pramlintide acetate is used alongside other antidiabetic agents, may also yield promising results. Additionally, ongoing studies aim to better understand its long-term effects and optimize dosing strategies to enhance patient compliance and outcomes.
In summary, Pramlintide acetate represents a vital component in the landscape of diabetes management and has the potential for broader applications in metabolic disorders and weight management.
| CAS Number | 196078-30-5 |
|---|---|
| Formula | C173H271N51O55S2 |
| Mol. Weight | 4009 g/mol |
| IUPAC Name | acetic acid;(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)... |
| Grade | HPLC ≥98% |
Synthesis & Storage
Pramlintide Acetate is supplied as a lyophilized powder to ensure stability during transit.
For long-term storage of CAS 196078-30-5, we recommend maintaining at -20°C.
Researchers must reconstitute this peptide with bacteriostatic water or sterile solvent only when ready for use.
Quality Control: All batches undergo rigorous HPLC purity testing (≥98%) prior to dispatch from our USA fulfillment center.