Vapreotide (CAS 103222-11-3) – Wholesale & Research Grade
Vapreotide, a synthetic analog of somatostatin, has gained attention in the field of medical research due to its multifaceted applications, particularly in the treatment of neuroendocrine tumors and other hormone-related disorders. This compound is often referred to by its synonyms, such as RC-160 or Somatuline, highlighting its relevance in clinical settings where somatostatin mimetics are utilized.
Research Applications
The principal application of Vapreotide lies in its ability to inhibit the secretion of various hormones, making it a valuable tool for managing conditions such as acromegaly, carcinoid syndrome, and certain types of gastrointestinal bleeding. Researchers are exploring its potential in the modulation of insulin and glucagon levels, which could open new avenues for diabetes management. Additionally, ongoing studies are investigating its role in the treatment of conditions associated with excessive growth hormone release and the alleviation of symptoms in patients with neuroendocrine tumors.
Mechanism of Action
Vapreotide exerts its therapeutic effects through binding to somatostatin receptors, which results in the inhibition of adenylate cyclase activity. This leads to a decrease in intracellular cAMP levels, ultimately reducing the secretion of various hormones and peptides. By mimicking the natural action of somatostatin, Vapreotide stabilizes hormone levels and alleviates symptoms in patients suffering from hormone-secreting tumors.
Solubility and Storage Advice
Vapreotide is soluble in water and should be stored in a cool, dry place, away from light to maintain its stability. Proper storage conditions are crucial to preserving its efficacy, and researchers are advised to consult specific product information for detailed guidelines on handling and storage.
Future Research Directions
Looking ahead, there is significant potential for Vapreotide in the realm of precision medicine, particularly in personalized therapies for cancer treatment. Future studies may focus on its combination with other therapeutic agents to enhance treatment outcomes for various malignancies. Additionally, ongoing research into its pharmacokinetics and long-term effects will contribute to a deeper understanding of its utility in clinical practice, paving the way for innovative applications in endocrinology and oncology.
| CAS Number | 103222-11-3 |
|---|---|
| Formula | C57H70N12O9S2 |
| Mol. Weight | 1131.4 g/mol |
| IUPAC Name | (4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-N-[(2S)-1-amino-3-(1H-indol-3-yl)-1... |
| Grade | HPLC ≥98% |
Synthesis & Storage
Vapreotide is supplied as a lyophilized powder to ensure stability during transit.
For long-term storage of CAS 103222-11-3, we recommend maintaining at -20°C.
Researchers must reconstitute this peptide with bacteriostatic water or sterile solvent only when ready for use.
Quality Control: All batches undergo rigorous HPLC purity testing (≥98%) prior to dispatch from our USA fulfillment center.